GenVec | GNVC | Profile | Summary
GenVec, (GNVC) is a biopharmaceutical company using differentiated, proprietary technologies to create superior therapeutics and vaccines. A key component of the company’s strategy is to develop and commercialize products through collaborations. GenVec is working with leading companies and organizations such as Novartis, Merial, and the U.S. Government to support a portfolio of product programs that address the prevention and treatment of a number of significant human and animal health concerns.
GenVec’s development programs address therapeutic areas such as hearing loss, balance disorders, and cancer; as well as vaccines against infectious diseases including respiratory syncytial virus (RSV), herpes simplex virus type 2 (HSV-2), dengue fever, influenza, malaria, and human immunodeficiency virus (HIV).
The GenVec’s Advantage
The company’s core technology has the important advantage of localizing protein delivery in the body. This is accomplished by using adenovector platform to locally deliver genes to cells, which then direct production of the desired protein. This approach reduces side effects typically associated with systemic delivery of proteins. For vaccines, the goal is to induce an immune response against a target protein or antigen. This is accomplished by using an adenovector to deliver a gene that causes production of an antigen, which then stimulates the desired immune reaction by the body.
GenVec’s novel proprietary adenovectors
No pre existing immune recognition
Built on rare human and nonhuman adenovirus serotypes
New GC technology shows superior performance for genetic vaccines
Multiple capsid modified vectors -AdH technology
Multiple genes/multiple antigens
Targeted and specific delivery Proprietary adenovectors and cell lines
Novel proprietary non replicating adenovirus vectors
Very low sero -prevalence in humans
Outstanding gene/antigen delivery properties
Cell line master banks and master file with FDA
Hearing Restoration Molecular Therapeutic
Dengue Virus Genetic Vaccine
Foot and Mouth Virus Genetic Vaccine
Malaria Genetic Vaccine
RSV Genetic Vaccine
HSV Molecular Therapeutic and Genetic Vaccine
A platform of adenovirus vectors built to meet product needs for molecular therapeutics and genetic vaccines
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